The New England journal of medicine 2018 06 26() doi 10.1056/NEJMoa1716435 Abstract Background The prognosis of patients with recurrent World Health Organization (WHO) grade IV malignant glioma is dismal, and there is currently...Read More
Author: Physicians Weekly
The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets.
Cell 2018 06 13() pii 10.1016/j.cell.2018.05.047 Abstract The inner nuclear membrane (INM) encases the genome and is fused with the outer nuclear membrane (ONM) to form the nuclear envelope. The ONM is contiguous with the...Read More
The Journal of clinical investigation 2018 06 26() doi 10.1172/JCI96393 Abstract Dormant or slow-cycling tumour cells can form a residual chemoresistant reservoir responsible for relapse in patients, years after curative surgery...Read More
Cell 2018 06 12() pii 10.1016/j.cell.2018.05.039 Abstract Many community- and hospital-acquired bacterial infections are caused by antibiotic-resistant pathogens. Methicillin-resistant Staphylococcus aureus (MRSA) predisposes...Read More
Nature communications 2018 06 199(1) 2404 doi 10.1038/s41467-018-04495-z Abstract A major hurdle in the study of rare tumors is a lack of existing preclinical models. Neuroendocrine prostate cancer is an uncommon and aggressive...Read More
Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts.
The New England journal of medicine 2018 06 13378(25) e34 doi 10.1056/NEJMoa1800389 Abstract BACKGROUND Observational cohort studies and a secondary prevention trial have shown inverse associations between adherence to the...Read More
International journal of molecular sciences 2018 06 0619(6) pii 10.3390/ijms19061689 Abstract Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy, which involves...Read More
Nature communications 2018 06 089(1) 2231 doi 10.1038/s41467-018-04651-5 Abstract CRISPR advances genome engineering by directing endonuclease sequence specificity with a guide RNA molecule (gRNA). For precisely targeting a gene...Read More
Frontiers in oncology 2018 05 248() 161 doi 10.3389/fonc.2018.00161 Abstract Advances in chemotherapy and targeted therapies have improved survival in cancer patients with an increase of the incidence of newly diagnosed brain...Read More